Known as the queen of Mexican beach resorts, Acapulco becomes one of the centers of Mexico's bloody drug war. And as a result, Holland America has dropped calls in Acapulco through 2018, citing security concerns.
The decision affects seven Panama Canal voyages and one South America sailing scheduled to take place starting in October.
Holland America said it would replace Acapulco with other ports in Mexico.
"The safety of our guests is our top priority," the line said in a statement about the schedule change. It said passengers on the affected sailings have been notified.